Biomarkers, Cytokines, and Chemokines
Biomarkers, Cytokines, and Chemokines Understanding the microenvironment within skin cancers is key for the development of new preventative and therapeutic treatment options. Research advances in skin cancers such as melanoma have revolutionized immunotherapeutic treatment options, for example through the provision of checkpoint inhibitor trials that have benefitted not just melanoma patients, but also patients with a wide array of other cancers, including less readily accessible cancer types. However, checkpoint inhibitor success is limited in melanoma and unlikely to become the mainstay of treatment for other skin cancer types like squamous cell carcinoma. Therefore, many skin cancer subtypes remain with few... Read More
Artificial Intelligence in Dermatology The increasing presence of artificial intelligence (AI) worldwide, has led to numerous attempts at leveraging such technology for challenging healthcare problems. In the field of dermatology, the most progress thus far, has taken place in the field of melanoma diagnosis. Multiple original articles and several reviews have been published demonstrating that camera systems with algorithmic processing abilities may be able to differentiate between nevi and malignant lesions with similar accuracy to certified dermatologists. Recognizing, however, that the field of dermatology is much broader than melanoma diagnosis, there is now a considerable number of additional topics under... 
CELL SCIENCE: CALL FOR PAPERS Journal of Cell Science and Mutation, a newly launched journal dedicated to the advancing Science and Gene Mutation. The journal publishes a wide range of scientific articles related to cell biology, multicellular, Cell theory, Cell movement, Ribosomes, Mitochondria, Cell division, Mutation, Gene therapy, Cell structures, Cell sciences along Human, Vegetative, Neurological stem cell, Nano technological stem cell research, Genetic Nano research , Tissue culturing, Chromosomes, Membranes, Eukaryotic cells,Cytoskeleton, Genetic material, Organelles, Eukaryotic, Eukaryotic and prokaryotic, Cell wall, Prokaryotic, Growth and metabolism, etc., Aims and Scope: Journal of Cell Science and Mutation (JCSM) main aim is... 
Internet has improved live and activities of human being in the society. Bringing digital changes to the way domestic and business activities are done with a special reference to shopping. This transformation from traditional shopping to online shopping in Nigeria is driven by the prevalence of internet connectivity in Nigeria. Nigeria has witnessed an improved growth in the usage rate of internet since the Nigeria communication commission launched GSM in 1999. In Nigeria, internet usage is driven more by the Smartphone and private laptops. Shopping in Nigeria is now advanced in line with the availability of internet. This has impacted... 
Manufacturing firms? performance is predisposed majorly to the strength of working capital management. Working capital management provides the strategy to improve financial strength and growth of firms. Considering the contribution of working capital to Jordan?s economy; this study examined the effect of working capital management on financial performance. Cross sectional and time series data of 46 listed manufacturing firms on Amman Stock Exchange for a period of 2010 to 2014 were assessed. This article conducted an empirical investigation using descriptive and regression analyses to evaluate the effect of working capital management on firms? financial performance. Multiple regression analysis was performed... 
Molecular Oncology 
The majority of microbes in many environments are considered “as yet uncultured” and were traditionally considered inaccessible for study through the microbiological gold-standard of pure culture. The emergence of metagenomic approaches has allowed researchers to access and study these microbes in a culture-independent manner through next generation sequencing and functional expression of metagenomic DNA in a heterologous host. Metagenomics has revealed an extraordinary degree of diversity and novelty, not only among microbial communities themselves, but also within the genomes of these microbes. Metagenomic analysis can involve sequence-based or functional approaches (or a combination of both). The continuous improvements to next-generation... 
Invasive species are increasingly recognized as key factors in the breakdown of ecosystem function, processes, and services, and loss of native biodiversity. The success of invasive species alters the dynamics of other species in the habitat leading to irreversible changes, ultimately with losses of native biodiversity that can impact the stability and resilience of the ecosystem, possibly by loss of functional traits associated with resource capture and decomposition. Invasive plant species are a global problem and the pace of biological invasions requires better early knowledge about the location of invaded communities, the invasive species responsible and the native composition of... 
The basic protective measure are: Wash your hands frequently Regularly and thoroughly clean your hands with an 
Characterization of giant mottled eel (Anguilla marmorata) gastrointestinal tract that origin from Thua Thien Hue, Vietnam 
Updates on Post-operative Delirium in Lumbar Degenerative Disease 
The Effect of Radiopacifier in Portland Cement for Repairing Furcal Perforations This study was designed to evaluater adiopacity, interface micrographs, and leakage mediated by zirconium oxide (ZO) placed into white Portland cement (PC) as a furcal perforation sealing material. Perforations were created in the floors of pulp chambers in 56 freshly human maxillary and mandibular molars and randomly divided into four experimental groups, each containing 12 teeth, and a negative control group containing 8 teeth. The experimental groups were prepared using 20% ZO plus PC, PC, ProRoot mineral trioxide aggregate (MTA), and 20% bismuth oxideplus PC. First, radiopacity was assessed... 
As the novel 
Author Name: Joel James Category Name: Medical Sciences Description: Importance of Biomedical Research Biomedical research claims high importance in understanding and accelerating the medical research and associated subjects. Considering the importance of human health and several emergency medical and clinical issues associated with it, prime attention towards biomedical research is of great significance. Thus, asserting the requirement of a common and enriched information sharing platform. Biomedical research is such unique platform to collect and disseminate state-of-the-art scientific understanding on biomedicine and related discipline. Scope The objective of the journal is to provide a scientific communication medium to discuss the utmost advancements in... 
Non-Coding RNAs Non-coding RNAs are critical molecules that constitute a substantial amount of the transcriptome. We have witnessed an ever-increasing repository of non-coding RNAs (ncRNAs) in the last decade, especially with the large scale application of high throughput sequencing technologies. These ncRNAs include, but are not limited to, miRNAs, siRNAs, long non-coding RNAs (lncRNAs), circular intronic RNAs (ciRNAs) and circular RNAs (circRNAs) originated from back-spliced exons. ncRNAs have been demonstrated to involved in all important biological processes and human diseases. However, our understanding of these ncRNAs are still at the initial stages, especially for newly found ncRNAs such as lncRNAs,... 
Zika Virus Recent outbreaks of Zika virus infections in South and Central America have led to an urgent need for research on the biological mechanisms and consequences of Zika infections. The local transmission of Zika virus has been reported in more than 50 countries and the situation was declared as a public health emergency of international concern by the World Health Organization, especially due to the possible causal link between Zika virus infection during pregnancy and the occurrence of microcephaly and other congenital malformations. In this Research Topic, we encourage the submission of original research reports, methods articles, perspectives, reviews... 
Antimicrobial resistance happens when microorganisms (such as bacteria, fungi, viruses, and parasites) change when they are exposed to antimicrobial drugs (such as antibiotics, antifungals, antivirals, antimalarials, and anthelmintics). Microorganisms that develop antimicrobial resistance are sometimes referred to as “superbugs”. As a result, the medicines become ineffective and infections persist in the body, increasing the risk of spread to others. Why is antimicrobial resistance a global concern? New resistance mechanisms are emerging and spreading globally, threatening our ability to treat common infectious diseases, resulting in prolonged illness, disability, and death. Without... 
The World health report 2010 estimated that about 20-40% of all health sector resources are wasted and highlighted health care leakages-waste, corruption and fraud-as the ninth leading source of inefficiency of health systems. The health care system of the United Arab Emirates (UAE) is currently ranked 9th out of 55 nations assessed by the Bloomberg’s health care efficiency index-the United States of America ranks 50th. However, if efficiency is defined conventionally based on costs to achieve specified outcomes, the UAE health system has efficiency shortcomings in relation to health care costs by its citizens for overseas medical treatment as well... 
Compensation benchmarking is the phenomenon of benchmarking a firm’s executive pay to that of the peer firms. In recent times, the practice of compensation benchmarking has gained a lot of traction. As a result, researchers are increasingly addressing the dynamics of compensation benchmarking among the firms. Compensation benchmarking is the phenomenon of benchmarking a firm’s executive pay to that of the peer firms. In recent times, the practice of compensation benchmarking has gained a lot of traction. As a result, researchers are increasingly addressing the dynamics of compensation benchmarking among the firms. There are two competing potential theories to explain compensation benchmarking.... 
Our 
Novel fact findings in corona virus WHO is gathering the latest scientific findings and knowledge on coronavirus disease (COVID-19) and compiling it in a database. We update the database daily from searches of bibliographic databases, hand searches of the table of contents of relevant journals, and the addition of other relevant scientific articles that come to our attention. The entries in the database may not be exhaustive and new research will be added regularly. During the current scenario, it is important to create more awareness in his field and more researches are needed to educate the people. GUIDELINES FOR AUTHORS... 
Shaping Genes, Genomes, Populations and Species Plants have evolved an incredible diversity of strategies to optimize their sexual reproduction. The physical distance between plant male and female organs varies from hermaphroditism to biparental reproduction. The investment of resources in different sexes is also extremely diverse. For example, male gamete dispersal can be wholly aspecific, relying on the mass production of pollen to saturate the environment and maximize the chances to encounter the maximum of receptive females through wind dispersal. On the contrary, it can be explicitly mediated by a single pollinator or targeted to a single female receiver via pollen... 
Journal of Food Nutrition & Health is a peer-reviewed scientific journal that offers pioneering research exploring the association of food and nutrition in promoting healthy living. Journal of Food Nutrition & Health offers scholarly research articles meant to create awareness on the ill effects of malnutrition by underlining the impact of food safety and security. It emphasizes the role of comprehensive diet in building strong immune responses to prevent and fight health disorders. Aims and Scope The journal focuses on a wide spectrum of topics in the fields including; Food, Nutrition, Diet, Vitamins, Minerals, Salts, Fats, Proteins, Carbohydrates, water, Eggs,... 
Journal of Food Nutrition and Health focuses on a wide spectrum of topics in the fields including; Food, Nutrition, Diet, Vitamins, Minerals, Salts, Fats, Proteins, Carbohydrates, water, Eggs, Legumes, Sea Foods, Vegetables, Fruits, Eating Disorders, Healthy Weight Management, Food Safety, Meal Management, Exercise, Physical activity, Malnutrition, Micronutrients, Macronutrients, Nutrition Deficiency, Non-nutritives, Food adjuncts and Drugs. The Journal publishes high-quality original articles, reviews, editorials, and case reports addressing all aspects of food and nutrition. It delivers timely interpretations of key scientific developments in food and nutrition in promoting healthy living and related areas of study. Known personalities with expertise and published... 
Author Name: Joel James Category Name: Medical Sciences Description: Why We Need Biomedical Research Biomedical research is the broad area of science that looks for ways to prevent and treat diseases that cause illness and death in people and in animals. This general field of research includes many areas of both the life and physical sciences. Utilizing biotechnology techniques, biomedical researchers study biological processes and diseases with the ultimate goal of developing effective treatments and cures. Biomedical research is an evolutionary process requiring careful experimentation by many scientists, including biologists and chemists. Discovery of new medicines and therapies requires careful scientific... 
Journal of Cardiovascular Medicine and Therapeutics is committed to dispersing unique and top-level original research articles, letters, perspectives, opinions, commentaries, case reports, reviews, letter to editor, editorials, and short communications etc. in every aspect of cardiovascular medicine. Journal of Cardiovascular Medicine and Therapeutics is using online Review and Editorial Manager System for quality review process of allied academies. Editorial Manager System is an online submission and review system, where authors can submit manuscripts and track their progress. Reviewers can download manuscripts and submit their opinions. Editors can manage the whole submission/review/revise/publish process. Publishers can see the manuscripts which are in... 
Journal of Cardiovascular Medicine and Therapeutics is committed to dispersing unique and top-level original research articles, letters, perspectives, opinions, commentaries, case reports, reviews, letter to editor, editorials, and short communications etc. in every aspect of cardiovascular medicine. The segment Cardiovascular Therapeutics is additionally concerned with the identification and validation of biomarkers to either help drug improvement, or permit a stratified medicine approach in patients. Biomarkers may identify with physiological measures,heredity qualities, or any of the developing advancements. Journal of Cardiovascular Medicine and Therapeutics is a peer reviewed, scholarly journal that gives a gathering to the most developed research and... 
Differences in quality attributes of sand smelt (Atherina hepsetus) fish burger and finger during frozen storage The present investigation has been carried out with the objectives study the effect of frozen storage on quality attributes of fish burger and fingers were made from sand smelt (bassaria) (Atherina hepsetus) with substitution levels from soybean flour and minced potato. Sand smelt has found in Qarun Lake by unaccepted from consumers. The physicochemical and microbiological analysis was carried on raw products immediately after processing and during frozen storage.Total Volatile Basic Nitrogen (TVBN), Trimethylamine (TMA), Thiobarbituric Acid (TBA) and pH values of sand smelt... 
Impacts of Moringa oleifera leaves and Lannea barteri bark as growth promoting additives and survival rates in the diets of Clarias gariepinus fingerlings 
The 
Cervical cancer happens when cells change in a woman’s cervix, which connects her uterus with her vagina. This cancer can affect the deeper tissues of her cervix and may spread to other parts of her body (metastasize), often the lungs, liver, bladder, vagina, and rectum. Most cases of cervical cancer are caused by infection with human papillomavirus (HPV), which is preventable with a vaccine. Cervical cancer grows slowly, so there’s usually time to find and treat it before it causes serious problems. It kills fewer and fewer women each year, thanks to improved screening through Pap tests. Cervical Cancer Causes... 
Invertebrates, as all other animals, rely on sensory input from their biotic and abiotic environment for survival and reproduction. Depending on the importance of a signal for a given species, accuracy of sensory coding might vary from pure detection up to precise coding of intensity, quality and temporal features of the signal. Investing energy in highly sophisticated sense organs and related central nervous processing areas can be of utmost importance in a complex environment and in animals using advanced communication systems. Peripheral and central sensory systems have therefore developed different anatomical and physiological features to optimally encode behaviourally relevant signals.... 
Cephalopod mollusks and decapod crustaceans are believed to the most developed and intelligent invertebrates and may be sentient animals. They are legally protected by a number of national and trans-national organizations, such as the European Union. In the proposed research topic we would start by attempting to define sentience/consciousness, probably in relation to what we understand in marine vertebrates, which may be very different from that in land-based forms. Given that many mollusks, including cephalopods, and crustaceans are model animals in neuroscience and species of interest for aquaculture, definitions and mechanisms of action of anesthetics and analgesics acquire an added... 
Investigation on Learning and Memory Enhancing activity of Essential Oil inAlbizia julibrissin Flowers in Experimental Mice 
Antidepressant and Skeletal Muscle Relaxant Activity of Methanolic Extracts of Basella alba. L 
Since 31 December 2019 and as of 28 March 2020, 5, 28, 025 cases of 
Acute pain has a physiological protective role in preventing tissue damage. However, pain can become chronic due to a multitude of pathophysiological states, such as: trauma, inflammation, neural injury, viral infection, cancer, autoimmune diseases and vascular and metabolic disorders. These pathological states can trigger alterations of the pain pathways that can lead to hypersensitivity, and in such circumstances, pain loses its protective role and instead, becomes persistent and debilitating affecting seriously to the quality of life of patients. Chronic pain is one of the most important health problems worldwide. It has been estimated that 10% of adults are diagnosed... 
Pain is a frequent symptom in leprosy patients. It may be predominantly nociceptive, as in neuritis, or neuropathic, due to injury or nerve dysfunction. The differential diagnosis of these two forms of pain is a challenge in clinical practice, especially because it is quite common for a patient to suffer from both types of pain. A better understanding of cytokine profile may serve as a tool in assessing patients and also help to comprehend pathophysiology of leprosy pain. Patients with leprosy and neural pain (n = 22), neuropathic pain (n = 18), neuritis (nociceptive pain) (n = 4), or no... 
People with an intellectual disability experience both acute and chronic pain with at least the same frequency as the general population. However, considerably less is known about the pain perception of people with Down syndrome. In this review paper, we evaluated the available clinical and experimental evidence. Some experimental studies of acute pain have indicated that pain threshold was higher than normal but only when using a reaction time method to measure pain sensitivity. However, when reaction time is not part of the calculation of the pain threshold, pain sensitivity in people with Down syndrome is in fact lowering than... 
Around 75% of cases of 
Cancer occurs when changes called mutations take place in genes that regulate cell growth. The mutations let the cells divide and multiply in an uncontrolled way. Breast cancer is cancer that develops from breast tissue. Typically, the cancer forms in either the lobules or the ducts of the breast. Lobules are the glands that produce milk, and ducts are the pathways that bring the milk from the glands to the nipple. Cancer can also occur in the fatty tissue or the fibrous connective tissue within your breast. The uncontrolled cancer cells often invade other healthy breast tissue and can travel... 
Can Increase In Temperature Kill COVID-19? Currently the most chronic disease Coronavirus can stay active for 8-10 days on dry surfaces and while it survives in the human body at 37 degree Celsius, they are heat labile like all viruses and are deactivated or destroyed when subjected to heat. The exact threshold temperature to deactivate COVID-19 is still unknown. Coronavirus: COVID-19 virus has now spread across over 110 countries with no known vaccine or cure. There has been a conjecture that increased temperature can kill the virus and that the onset of summer will lead to a breakdown in transmission... 
Despite extensive investigation, the cause of IPF remains unknown.The fibrosis in IPF has been linked to cigarette smoking, environmental factors (e.g. occupational exposure to gases, smoke, chemicals or dusts), other medical conditions including gastroesophageal reflux disease (GERD), or to genetic predisposition (familial IPF). However, none of these is present in all people with IPF and therefore do not provide a completely satisfactory explanation for the disease. IPF is believed to be the result of an aberrant wound healing process including/involving abnormal and excessive deposition of collagen (fibrosis) in the pulmonary with minimal associated inflammation. It is hypothesized that the initial or repetitive injury in IPF occurs to the... 
Molecular Medicine Atomic prescription is an expansive field which manages the improvement of illnesses at a sub-atomic level and distinguishes crucial sub-atomic and hereditary blunders of 
Treatment of 
World Health Organization declared an outbreak of febrile 
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The first is that a team of researchers from various institutions in Nigeria, including scientists from the Centre for Human and Zoology Virology in LUTH, African Centre for Genomics of Infectious Diseases in Redeemers University and the Nigeria Institute of Medical Research (NIMR) Lagos, combined their efforts to successfully perform the genome sequencing of the coronavirus strain that the index case brought to Nigeria and proved it to be a match with the virus circulating in Italy and Wuhan. This was coordinated by the Lagos State Ministry of Health and NCDC. It is the first time the sequencing of... 
Endocrinology and Diabetes 
Gift tax is a direct tax in nature which is levied on the taxable gifts under Gift Tax Act-1990 that was adopted from Pakistani Gift Tax Act 1963 with some modifications in Bangladesh. In some countries gift tax and inheritance tax is one and the rate of inheritance tax depends on the closeness of the relationship. Gift consists of the extinction of one’s own property and the generation of another property, that can also be termed as present and Gift tax is paid on the gifted money or money’s worth. Gift tax is digressive in structure of tax rate. Generally... 
This study examined the relationship between accounting information and management decision with emphasis on the effect of accounting information on economic order quantity decision, human resources management decision and marketing decision of selected manufacturing organizations. Data were sourced primarily with the aid of structured questionnaire from one hundred and fifty top management staff statistically selected from the selected manufacturing companies in Osun State, Nigeria. Empirical research designs and inferential analysis were carried out with the aid of statistical package for social sciences (SPSS version 20). The t-test results carried out confirmed a positive relationship between accounting information and management decisions... 
Impacts of Moringa oleifera leaves and Lannea barteri bark as growth promoting additives and survival rates 
Unique non-oxygen breathing animal discovered The tiny, less than 10-celled parasite Henneguya salminicola lives in salmon muscle. As it evolved, the animal, which is a myxozoan relative of jellyfish and corals, gave up breathing and consuming oxygen to produce energy. "Aerobic respiration was thought to be ubiquitous in animals, but now we confirmed that this is not the case," Prof. Huchon explains. "Our discovery shows that evolution can go in strange directions. Aerobic respiration is a major source of energy, and yet we found an animal that gave up this critical pathway." "Aerobic respiration was thought to be ubiquitous in animals, but... 
Pharmacognostical Screening and Phytochemical Evaluation of Albizia lebbeck Benth. Heartwood 
Biodegradable Polymers, Role in Enhancing Bioavailability of Drug 
Our 
The
Non-mammalian animals are useful models for understanding the evolution of the immune system and studying the underlying mechanisms of cellular and molecular responses in mammalian immunity. In 1882, Elie Metchnikoff discovered cells surrounding a wound in starfish larvae and named them “phagocytes” based on his hypothesis that these cells surround and kill pathogens. Recent literature has expanded the function of phagocytes beyond pathogen killing to the regulation of the overall inflammation response. In humans, many diseases, including congenital neutropenia, familial Mediterranean fever, and sepsis, stem from dysregulated phagocyte function, with no satisfactory treatment regimens currently available. Because of the high... 
Radiation therapy is a type of cancer treatment that uses beams of intense energy to kill cancer cells. Radiation therapy most often uses X-rays, but protons or other types of energy also can be used. Radiation therapy damages cells by destroying the genetic material that controls how cells grow and divide. While both healthy and cancerous cells are damaged by radiation therapy, the goal of radiation therapy is to destroy as few normal, healthy cells as possible. Normal cells can often repair much of the damage caused by radiation. Risks Radiation therapy side effects depend on which part of your body is being exposed to... 
Being a Managing Editor to 
Medical Device Connectivity Market Consumption Sales By Type, Product Specifications, Market Research Methodology, Market Forecast To 2023 Global Medical Device Connectivity Market Report 2019 – Market Size, Share, Price, Trend and Forecast is a professional and in-depth study on the current state of the global Medical Device Connectivity industry. The report also covers segment data, including: type segment, industry segment, channel segment etc. cover different segment market size, both volume and value. Also cover different industries clients information, which is very important for the manufacturers. There are 4 key segments covered in this report: competitor segment, product type segment, end... 
This paper investigated the dynamic interrelationship between macroeconomic fundamentals and stock prices in Nigeria using time series data spanning from 1980 to 2016. The study made use of co-integration test and the error correction mechanism. Empirical estimates revealed pointedly that there is a long run correlation between macroeconomic fundamentals and stock prices in Nigeria. Similarly, in the short run, the previous values of money supply and interest rate were found to demonstrate a significant effect on stock prices. Also, the previous value of stock market return was found to show significant influence on the current stock prices. Markedly, the results... 
Assessment of 
This research uses descriptive analysis method. The descriptive method of analysis is strengthened by observation and survey. This research uses non probability sampling sampling method, that is judgment sampling. The sampling technique was chosen to obtain sampling units that had the desired characteristics and snowball sampling aimed to determine the information of the respondents. Data analysis techniques using Linear Interactive and Discrete Optimize (LINDO). Linear Interactive and Discrete Optimizer is an interactive programming package of linear, quadratic and integral programs. The results showed that : Based on the calculation of sensitivity analysis using LINDO, the allocation of rice from the... 
Horizontal Carousel Market Size 2020: Research Methodology, Top Manufactures and Market Size Estimate 2025 This elaborate and detailed research output on Global Horizontal Carousel Market is an illustrative narrative on ongoing market developments and advances that have a lingering effect on growth estimations and growth patterns in the Global Horizontal Carousel Market. This comprehensive research offering is strategically designed to focus intrinsically on various market factors that fetch high return on investments and pave way for lucrative avenues in the Global Horizontal Carousel Market through the forecast span. Additionally, this Global Horizontal Carousel Market industry report gauges closely remunerative trends... 
The Importance of Biomedical Research on Emerging Health Trends 
Biomedical research partners with Research Institutes to improve research sharing 
Cancer of the lung, like all cancers, results from an abnormality in the body's basic unit of life, the cell. The lung is a very common site for metastasis from malignant tumors in other parts of the body. Lung cancers can arise in any part of the lung, but 90%-95% of cancers of the lung arise from the epithelial cells, the cells lining the larger and smaller airways (bronchi and bronchioles); for this reason, lung cancers are sometimes called bronchogenic cancers or bronchogenic carcinomas. (Carcinoma is another term for cancer.) Cancers also can arise from the pleura (called mesotheliomas) or... 
Dental Caries: A Review 
Viral Infection (Lymphocystis) in Fish Lymphocystis Disease Lymphocystis disease is a common viral infection which affects the skin and fins of saltwater and freshwater fish. Although it is serious, it does not cause any health problems; the disease only disfigures the fish. Fishes kept in aquariums or outside in ponds are both susceptible to Lymphocystis disease. The painted glassfish is the most prone aquarium fish to contract this infection. Symptoms and Types The viral infection causes growths on the skin or fins, which look similar to cauliflowers. The Lymphocystis disease does not pose any health problem to the fish, but... 
New Tank Syndrome in Fish Similar to "old tank syndrome," new tank syndrome is a fish disease that occurs in aquarium fish that live in water with high levels of ammonia. Symptoms New tank syndrome leads to ammonia toxicity in the fish, which can quickly become fatal. Fish will often die suddenly, without warning. The aquarium water is frequently cloudy and smelly due to the excessive ammonia and nitrite levels. Causes Also known as the "break in cycle," the cause of the high levels of ammonia in a new tank are due to the lack of beneficial bacteria in the... 
The term "
An important area of clinical 
Transfusions in companion animals such as dogs, cats and horses are frequently done in veterinary medicine as life-saving procedures and as part of the treatment protocol of many hematological, coagulation, and immunological disorders. Companion animals have many blood groups and blood types and some blood typing tests are available for their determination. However, many other blood types are suspected to exist and methods for typing are not always readily available. Studies on new blood type and cross matching methods and on epidemiology of blood groups could improve knowledge of blood groups in companion animals and improve quality of veterinary transfusion... 
Intravenous fluids are one the most commonly administered treatments in veterinary medicine. Fluids are drugs that are capable of producing marked changes in hemodynamic, electrolyte, acid-base, hematologic and coagulation profiles dependent upon the fluid type (i.e. crystalloid, colloid), volume, rate and timing of fluid administration. Appreciation of the physiologic relevance of blood volume distribution (i.e. stressed, unstressed), the endothelial glycocalyx and lymphatic system during health and disease (ex. hemorrhage, trauma, sepsis) has revised understanding of capillary fluid and solute exchange and resulted in context-sensitive volume expansion. This approach in conjunction with appropriate use of vasopressors and the employment of improved... 
The social media phenomenon has opened up new paths of engagement and revolutionized the way people exchange information. As social media technology continues to evolve and becomes more widespread, it presents an exciting opportunity for the recruitment industry. This writing reflects on issues concerning social media recruitment in private sector and it aims to raise the awareness of businesses and HR professionals on how the use of social media can positively impact the recruitment process, and how social media could serve as a potential tool for recruitment. In the context of the contemporary global business environment, the role of social... 
Given the changing realities of the business environment, supply chain issues have become one of the top priorities of CEOs in different firms. Growing attention to supply chain networks also highlights the importance of using efficient supply chain management practices. The belief that supply chain management can lead to continuous improvement of corporate performance has led CEOs to focus on upgrading the supply chain management process. The main objective of this research is to evaluate the impact of supply chain capabilities on operational and financial performance of food companies. The study population consists of 76 companies operating in the food... 
Cancer Science 
Impacts that threaten or indeed compromise the integrity of tissues trigger the development of a defence response, which through the activity of the nociceptive system includes pain. If the noxious impact does not induce tissue damage, the pain, called “nociceptive” pain, ceases within seconds after the impact is withdrawn. In contrast, if tissue damage does occur, a pain experience that usually persists until the injury is resolved and includes two major pathological sensory experiences, hypersensitivity to heat stimuli (i.e. heat hyperalgesia) and/or hypersensitivity to mechanical stimuli (i.e. mechanical allodynia) develop. The cellular and molecular mechanisms underlying the development of... 
For a long time, resident innate immune cells in central and peripheral nervous system, such as macrophages/microglia and mast-cells, have been considered as contributing players in peripheral neurodegeneration. New evidence seems to indicate that this view represented an underestimation of the role of inflammation in the nervous system, attributing to neuroinflammation a critical role of primary driver in peripheral neuropathies and pain. This is the case for autoimmune neuropathies (i.e. Guillain–Barré syndromes), diabetic neuropathy or traumatic nerve injury. Since neuropathic pain, the major feature of the most inflammatory neuropathies, is strongly influenced by the release of proinflammatory cytokines in response... 
Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, and immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy. 
Kidney and Urinary Tract Disorders in Fish There are few major kidney and urinary tract disorders seen in fishes. Of these the main kidney and urinary tract disorders are Renal Dropsy, Carp-dropsy complex, and Proliferative kidney disease (PKD). Renal dropsy in fishes is caused by the parasite, Sphaerospora auratus. Renal dropsy usually occurs in pond-raised goldfish. There is damage to the kidneys and swelling of the abdomen due to fluid accumulation is the most common sign of renal dropsy. There is no treatment for this kidney disorder and it usually causes death of the infected fish. Carp-dropsy complex is a... 
Gas Bubble Disease in Fish Gas Bubble Disease in Fish Gas bubble disease refers to the development of gases in a fish's bloodstream. This can occur when its aquarium or pond water is supersaturated with gases. Symptoms and Types Gas bubble disease damages the fish's tissue, causing tiny gas bubbles to form in the gills, fins, and eyes of the animal. This tissue damage, if extensive, can even lead to the fish's death. Causes Fishes are cold-blooded creatures, meaning their body temperature depends on the temperature of their environment. The water they live in and their bloodstreams can become supersaturated with... 
The pregnancy is told as a rare event among 
While 
Azaphilones: Their Role in Various Biological Activities 
Marine megafauna are iconic and charismatic. The threatened or endangered status of many species, the great economic importance of some taxa and their frequent role as keystone species in ecosystems has resulted in many becoming flagships for research by both professional and citizen scientists. The body size and mobility of marine megafauna means that their populations tend to be spread across wide ranges, multiple management jurisdictions and national boundaries. In contrast, research efforts are often compartmentalized, separated by both geography and approach. These barriers to progress have begun falling away in recent years, as researchers recognize the imperative to pool... 
Mesosaurs are among the most amazing extinct animals; they are the oldest known reptiles that developed aquatic adaptations, although how terrestrial their ancestors had become remains to be established; they are the only known vertebrates from Gondwana at the Early Permian and they are represented by thousands of well preserved and almost complete skeletons. Mesosaurs were capable of inhabiting cold and salty water bodies resulting from the drought of an originally large inland sea that extended over what is now South America and Africa. So far, mesosaurs are the only tetrapods known from a depauperate ecosystem that included pygocephalomorph crustaceans,... 
Exercise and Sports Medicine Exercise is significant to health and well-being. The introduction of exercise and physical activity into daily life promotes health, fitness, strength, endurance, performance, and quality of life. I would like to know your interest and time in submitting an article for the upcoming issue of 2020. You may submit your papers as an attachment to this email or online at: https://www.scholarscentral.org/submission/allied-medical-research.html. How we work: After submission, an acknowledgement with manuscript number is sent to the corresponding author within 7 working days. A 21 day window time frame is allotted for peer-review process wherein multiple experts... 
UNCOVER NOVEL FACT FINDINGS WITH BIOMEDICAL RESEARCH 
Our understanding of Mesozoic birds has expanded and evolved enormously over the past two decades, reflecting important discoveries from around the world. Most recently, information from 99-Ma-old birds trapped in Burmese amber is complementing the wealth of data extracted from Early Cretaceous Lagerstätten in China and Spain. Expanding knowledge of early avian morphological diversity, combined with inferences derived from exceptionally preserved soft tissues, is rapidly changing our perception of stem avians, revealing unexpected complexity and homoplasy in both the transition from non-avian dinosaurs to birds and the evolution of the crown avian condition, and providing unprecedented insights into the biology... 
Weather conditions affect animals in many different ways. Variation in temperature, rainfall, wind, and other environmental variables can have an impact at a range of temporal and spatial scales and at every level from individual behavior to species distributions. The interactions between these variables may be particularly important but are often overlooked. Hence, understanding how animals respond to weather conditions is a fundamental topic in evolution, ecology, and conservation, especially in a time of major environmental change. Birds are an ideal group in which to investigate these relationships because they occur in almost every ecosystem across the globe, exploit a... 
Cancer Science 
Microbiology of Dental Caries Dental caries can be defined as a localised and chemical loss of the tooth structure caused by the metabolic activity of dental biofilm that covers the tooth surface. This loss is reversible, especially in its early stages. The final outcome of dental caries is determined by multiple factors such as saliva, exposure to fluoride, and sugar dietary consumptions, which influence the dynamic balance between the demineralisation and remineralisation processes. Dental caries can be developed in any part of the tooth surface: enamel, dentine or cementum. However, it is more common in the sites wherein the dental... 
Microbial Biotechnology Microbes (or microorganisms) are organisms that are too small to be seen by the unaided eye. The wide variety of microbial habitats reflects an enormous diversity of biochemical and metabolic traits that have arisen by genetic variation and natural selection in microbial populations. Research in the Department of Microbial Biotechnology focusses on microbes of environmental, industrial or clinical relevance. Our work includes several approaches based on molecular genetics, systems and synthetic biology, genomics, proteomics and metagenomics. The scientific objectives of the department include five complementary aspects of microbial biology: Environmental Microbiology: We study the regulatory mechanisms that degrade... 
This paper provides an overview on the viability and performance of bitcoins as a payment alternative. The history of the Crypto-currency is briefly covered followed by the operation and potential technology failure. The paper then discusses consumer acceptance of bitcoins by analyzing a survey conducted by and the positive and negative observation of the results will be discussed. Fiat Currencies, Traditional E-commerce and Alt-Coin are identified as bitcoins direct competitors and a comparison done on bitcoins against its competitors. The regulatory issues and the legality of bitcoin are also discussed. For many years, financial intermediaries play an important... 
This paper investigated the dynamic interrelationship between macroeconomic fundamentals and stock prices in Nigeria using time series data spanning from 1980 to 2016. The study made use of co-integration test and the error correction mechanism. Empirical estimates revealed pointedly that there is a long run correlation between macroeconomic fundamentals and stock prices in Nigeria. Similarly, in the short run, the previous values of money supply and interest rate were found to demonstrate a significant effect on stock prices. Also, the previous value of stock market return was found to show significant influence on the current stock prices. Markedly, the results... 
Fish Lice and Leeches Whether fish live in an aquarium, a pond, or in saltwater, they are at risk for being infected by parasites. Some parasites are particular to the type of water, but one parasite that infects fish living in all three types of water is the protozoan parasite Ichthyobodo. Reasons for Ichthyobodo infection The most common instigator of this protozoan parasite infection is stress due to poor sanitary conditions and overcrowding of the aquarium, tank or pond. Stress leads to a weakened immune system, which leads to vulnerability to this parasite. Even overfeeding can stress the fish and lead to parasitic... 
Herpesvirus Diseases in Fish Herpes virus is not only a human virus; it can just as easily infect fishes, too. In fishes, herpes virus infections can cause a variety of diseases; including those can be fatal to the animal. Channel Catfish Virus (CCV) is a serious herpes virus infection in the fry and fingerling -- both fish young -- of the channel catfish. CCV usually infects weak fishes that are stressed due to shipping and handling, a lack of oxygen in the water, or chemically treated water. Fishes which are older have higher survival rates than younger fishes, and those... 
Supra-trochlear foramen and its clinical significance 
Tumor cells have developed various mechanisms to escape immune surveillance • CD8+ cytotoxic T cells are a fundamental element of anti-tumor immunity. Their TCR receptors recognise antigens presented by MHC class I and when bound, the Tc cell triggers its cytotoxic activity. MHC I are present on the surface of all nucleated cells. However, some cancer cells lower their MHC I expression and avoid being detected by the cytotoxic T cells. This can be done by mutation of MHC I gene or by lowering the sensitivity to IFN-γ (which influences the surface expression of MHC I). Tumor cells also... 
The beauty of the skin is that you can affect it from both inside and out. Eating plenty of 
Journal of Cardiovascular Medicine and Therapeutics is a monthly Open Access Publication. It publishes original research articles, epidemiological studies, new methodological clinical approaches, case reports, design and goals of clinical trials, review articles, points of view, editorials and Images in cardiovascular medicine. Submitted articles undergo a preliminary review by the editor. Articles being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool. The Cardiovascular Diseases affecting the developed world have at their core atherosclerosis and Hypertension, both of which are profoundly affected by diet... 
Insights of Dosage form Design: Polymorphs and Cocrystals Formulators are charged with the responsibility to formulate a bioequivalent product (in case of ANDA) product which is physically and chemically stable, manufacturable at commercial scale. Different crystal structures in polymorphs arise when the drug substance crystallizes in different crystal packing arrangements and/or different conformations. Besides, Polymorphs cocrystallization is now important method to achieve crystalline forms of molecules where alternative polymorphs or salts or solvates are desired. Regulatory road map for polymorphs approval is quite clear and for cocrystals draft guidance is on scientific advisory form public. From Intellectual property perspectives polymorphs... 
Nanopharmaceuticals: A New Perspective of Drug Delivery System 
What Causes Fish-Handler's Disease? The disease has so many names because so many different outbreaks have been associated with occupations (fishermen or lobstermen), hobbies (tropical fish tanks, pet shop workers), or water sports (boating, swimming pool use). Researchers also discovered that at least two different genera of bacteria (Mycobacterium and Erysipelothrix) were the main causative infective agents of the disease. These findings added to the proliferation of names. Causes Fish-Handler's Disease This is an erysipeloid infection, which means it is caused by an infection which resembles erysipelas but is caused by a different organism than that which causes erysipelas. Handling... 
The impact of Renin-angiotensin system blockers on lung cancers prognosis Background and objective: The impact of antihypertensive medications angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on the clinical outcomes of lung cancer patients remains controversial. This meta-analysis was conducted to investigate the association between ACEIs/ARBs usage and survival of lung cancer patients. Methods: Eligible studies were identified by searching Pubmed, Embase and Cochrane library up to February, 2017. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated for the effect of ACEIs/ARBs on survival of lung cancer. Heterogeneity and sensitivity were also analyzed. Results: We finally... 
Metal levels in commercial pelagic fishes and their contribution 
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Network meta-analysis of the effectiveness of various drugs in preventing allergic hypersensitivity in patients after anesthesia Objective: To explore the effect of different drugs on postoperative hyperalgesia in general anesthesia patients. Methods: A randomized controlled trial was conducted to detect the hyperalgesia of patients with general anesthesia from PubMed, Embase, Medline, CNKI and Wanfang databases. The visual analogue scale (VAS) assessment of hyperalgesia patients after anesthesia was extracted as well as the effects of various prophylactic agents on the incidence of side effects in postoperative patients. Multivariables meta-analysis was performed by Stata 14.0 software to explore the effectiveness of various... 
Cancer Cell Biology & Genetics 
During the past few years, mammalian development has been extended in vitro beyond the pre-implantation and post-implantation period. The exploitation of three dimensional (3D) culture systems has allowed to recapitulate gastrulation and, with the creation of organoids that summarize the process of organogenesis, to mimic the cellular organization and function of specific tissues and organs. The most recent advancements in computing science coupled with molecular technologies allowed a tremendous leap forward in our capacity to characterize the molecular networks of a large number of cell types. In addition, the evolution of imaging instruments and tools is radically changing the... 
Adjuvant 
The objective of this paper is to analyze the performance of 10 selected deposit money banks in Nigeria using the simple random sampling technique over a period of fifteen years (2000-2015). The data were sourced from the audited annual reports from the Nigerian Stock Exchange. For this purpose, CAMELS model was used. The CAMELS model established that six of the banks namely; Banks A, B, C, D, E and G were graded as satisfactory (scale point 2) in their general performances based on the 5 point likert scale where 1 is the highest and 5 is the lowest whereas 4... 
This study sets out to examine the effects of financial leverage on the profit growth in Nigeria using the total debt to capital ratio, debt to equity ratio, cost of debt, debt to asset ratio and long term debt to capital ratios as proxies for financial leverage for a sample of 80 non-financial firms quoted on the Nigerian Stock Exchange over the period of 2000 to 2015. Data were analysed using the panel data regression analysis model which includes the pooled regression model, fixed effect model and the random effect model. The choice of the appropriate model between Fixed Effect... 
Although the topic of animal personality has generated much interest in recent years, the role of development is little understood. This collection of papers will deal with the development of animal personality. Topics will include the roles of the genetics and evolution of the development of personality, maternal and paternal effects, the potential role of predation risk, acoustic and visual effects, conspecific effects, and other environmental effects such as temperature. The organisms covered will include invertebrates such as insects, fishes, mammals, reptiles and birds. Contributors will include both beginning and experienced investigators in the field of animal personality. Personality traits... 
Marine megafauna are iconic and charismatic. The threatened or endangered status of many species, the great economic importance of some taxa and their frequent role as keystone species in ecosystems has resulted in many becoming flagships for research by both professional and citizen scientists. The body size and mobility of marine megafauna means that their populations tend to be spread across wide ranges, multiple management jurisdictions and national boundaries. In contrast, research efforts are often compartmentalized, separated by both geography and approach. These barriers to progress have begun falling away in recent years, as researchers recognize the imperative to pool... 
Pathogenicity Pathogenicity refers to the ability of an organism to cause disease (ie, harm the host). This ability represents a genetic component of the pathogen and the overt damage done to the host is a property of the host-pathogen interactions. Commensals and opportunistic pathogens lack this inherent ability to cause disease. However, disease is not an inevitable outcome of the host-pathogen interaction and, furthermore, pathogens can express a wide range of virulence. Virulence, a term often used interchangeably with pathogenicity, refers to the degree of pathology caused by the organism. The extent of the virulence is usually correlated with the... 
Oncology: 
When the body's control mechanism disruptions working properly and the cells remain no longer normal, they start growing abnormally and uncontrollably, hence causing Cancer. Old cells do not die and as an alternative grow out of control, forming new, 
On Earth, human activities are changing the 
It is when a functional food aids in the prevention and/or treatment of disease and/or disorder(s) other than anemia, it is called a 
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria and antifungals are used against fungi. They can also be classified according to their function. Agents that kill microbes are called microbicidal, while those that merely inhibit their growth are called biostatic. The use of antimicrobial medicines to treat infection is known as antimicrobial chemotherapy, while the use of antimicrobial medicines to prevent infection is known as antimicrobial prophylaxis. The main classes of antimicrobial agents are disinfectants... 
Swim Bladder Disorder in Aquarium Fish Swim bladder disease, also called swim bladder disorder or flipover, is a common ailment in aquarium fish. The swim bladder is an internal gas-filled organ that contributes to the ability of a fish to control its buoyancy, and thus to stay at the current water depth without having to waste energy in swimming. A fish with swim bladder disorder can float nose down tail up, or can float to the top or sink to the bottom of the aquarium. Symptoms of Swim Bladder Disorder Fish suffering from swim bladder disorder exhibit a variety of... 
Apprehensions and issues related to pacu Piaractus brachypomus farming in India 
Comparative Study of Liver Enzymes Activities in Smokers and Diabetic Sudanese Patients 
Glucose Caffeine Combo Can Improve Brain Activity Efficiency According to a study, a glucose and caffeine combination can improve brain activity efficiency. Neural substrate for the combined effects of these 2 substances was identified making use of functional magnetic resonance imaging. The main study results were that the 2 substances combined improve cognitive performance in terms of working memory and sustained attention by increasing brain activity efficiency in the brain regions responsible for these 2 functions. This supports the notion of a synergistic effect between 2 substances, in which the effect of each one is boosted by the other. The... 
Age-related macular degeneration (AMD) is an ocular condition which may get worse over time. It is the leading cause of extreme, permanent loss of vision in persons over 60 years old. This occurs when the small central portion of your retina, called the macula, wears down. Early symptoms of dry AMD include slightly blurred vision, the need for more reading light, and difficulty in recognizing faces until they are very close to the person. Smoking, high blood pressure, obesity, a diet high in unsaturated fats, simple carbohydrates and lack of exercise all contribute to the risk of AMD. Good eye... 
Basic ECG Management Software Functionality 
Nicotine replacement therapy and varenicline: A cohort study in low-income region (Monastir, Tunisia). Background: Among motivated Smokers, cessation can be performed by Nicotine Replacement Therapy (NRT), or by Varenicline (VAR). We aimed at determining quit rates among two cohorts, treated by NRT or VAR and, at identifying factors associated to quit and relapse delays. Methods: We carried out a prospective cohort study at the smoking cessation center of the University Hospital of Monastir, in Tunisia from April 2009 to January 2012. Results: 1042 active smokers have been followed in smoking cessation center between April 2009 and December 2010. One hundred... 
In this study, I examine the relation between the cash conversion cycle and its components and a firm’s diversification status. Using a large sample of US public firms over 1980 to 2016, I find the inventory and receivable periods are shorter in diversified firms than focused firms. The results suggest that diversified firms have more efficient inventory management; and have better access to external financing which makes supply chain financing less significant in diversified firms. There is evidence that diversified firms have longer cash conversion cycle, especially in more recent sample years. Further research... 
The true and fair view in much Italian company is not applied in financial reporting. The company often applies a different principle which is affected by tax legislation. This “new” principle can be called: the “tax true and fiscally fair” principle. An empirical research I conducted in Italy has shown that Italian financial statements are “contaminated” by regulations that differ from accounting standards. In fact, many Italian financial statements are not prepared according to national and/or international accounting standards, but rather based on tax laws upon the occurrence of fiscal interference in the final financial statements assessments, the balance sheet... 
Genome instability (also genetic instability or genomic instability) refers to a high frequency of mutations within the genome of a cellular lineage. These mutations can include changes in nucleic acid sequences, chromosomal rearrangements or aneuploidy. Genome instability does occur in bacteria. In multicellular organisms genome instability is central to carcinogenesis,and in humans it is also a factor in some neurodegenerative diseases such as amyotrophic lateral sclerosis or the neuromuscular disease myotonic dystrophy.The sources of genome instability have only recently begun to be elucidated. A high frequency of externally caused DNA damage can be one source of genome instability since DNA damages can cause inaccurate translesion synthesis past the damages or errors in repair, leading to mutation. Another source... 
Molecular phenotyping describes the technique of quantifying pathway reporter genes, i.e. pre-selected genes that are modulated specifically by metabolic and signaling pathways, in order to infer activity of these pathways. In most cases, molecular phenotyping quantifies changes of pathway reporter gene expression to characterize modulation of pathway activities induced by perturbations such as therapeutic agents or stress in a cellular system in vitro. In such contexts, measurements at early time points are often more informative than later observations because they capture the primary response to the perturbation by the cellular system. Integrated with quantified changes of phenotype induced by the perturbation, molecular phenotyping can identify pathways that contribute to the... 
Isolation and identification of Citrobacter spp. from the intestine of Procambarus clarkia 
The shelf-life of Macrobrachium nipponense dried meats during six months storage at room temperature 
Analysis of Some Morphometric Parameters of Tibia 
Self-Care and Related Factors in Patients with Type 2 Diabetes One of the factors that control the complication of 
Swimming is an integral aspect of the life history of many fish species in the aquatic environment. Teleost fish show a great variety of locomotor strategies that are linked to their feeding behavior, predator avoidance, environmental (e.g. light, temperature, salinity, depth, etc.) preferences, social and reproductive behaviors, etc. The most dramatic examples of locomotor strategies can be found among those species that undergo long and lengthy reproductive and feeding migrations, such as salmonids, thunniforms and anguillids. From an organismic point of view, swimming is a behavior that occurs in intimate relation to other biological processes that fish experience throughout their... 
Structure and mechanism of Fingolimod 
Quantitative genetic studies Gene–environment and its significance 
After decades of steady decline, the number of deaths from cardiovascular disease (CVD) has risen over the past few years, according to the American Heart Association. The good news is that an estimated 80% of all CVD cases — heart disease, heart attack, heart failure, and stroke — can be prevented. The key is to control high blood pressure and high cholesterol and to maintain healthy habits, such as exercising regularly, eating a plant-based diet, getting enough sleep, and not smoking. No surprise, right? This advice has been consistent for many years. But the best way to meet these standards... 
The importance of 
The world’s population is predicted to hit 9 Billion by 2050, and with it food demand is predicted to increase substantially. The World Bank estimates that cereal and meat production needs to increase by 50% and 85% respectively between 2000 and 2030 to meet demand, putting serious pressure on the global agricultural industry. Critical to meeting this demand for food are mechanisms to reduce the incidence of animal disease. Within excess of 1.3 billion cattle globally, the total cost of infectious diseases is difficult to estimate. However in North America alone, the cost is predicted to be $18 billion annually.... 
The ability to sequence entire genomes and transcriptomes is revolutionising cancer biology and, more slowly, cancer medicine. The evidence that large‐scale sequencing has clinical utility, that it improves outcomes, is slowly accumulating. A major controversy has centred on whether or not all tumours refractory to standard therapy should undergo therapy selection by molecular genetic cancer profiling (MGCP). Despite several completed or ongoing clinical trials, this issue is not settled; however, other forces now ensure that MGCP will become a routine diagnostic tool. Biopsies are becoming smaller, providing greater safety for patients, but yielding less DNA/RNA while there are now sufficiently... 
Pediatric phase I oncology trials have historically focused on safety and toxicity, with objective response rates (ORRs) <10%. Recently, with an emphasis on targeted approaches, response rates may have changed. Authors analyzed outcomes of recent phase I pediatric oncology trials. 
The Journal of Molecular Oncology Research is an open access peer-reviewed journal it reaches more number of readers with high quality research content based on Clinical Oncology practice, including administration, pharmacokinetics, preoperative and postoperative considerations, coexisting disease and other complicating factors, Cancer Surgery, Orthopedics cancer, GI cancer, Cancer Neurosurgery, Cancer Cardiothoracic, Cancer Vascular Surgery, Cancer Urology, Surgical Oncology. Our 
Journal of Molecular Oncology Research is a peer-reviewed Open Access Journal, encourages on-going international research and articles related to Oncology. It’s our privilege to recite you as a foremost strategist in the realm of research and invite you to endowment your research penmanship and publication in forth coming issue in the form of Research, Reviews, Commentaries, Letter to Editor, Case Reports, Short Communication, Images, Conference Proceedings which will be published in our journal. 
The Journal of Finance and Marketing disseminates high quality research content based on Financial Marketing from marketing professionals across the globe, with implications from the leading Business schools, universities and research institutes. Our 
The 
Preparing medical graduates in Sri Lanka for a productive internship and beyond: The “Good Intern Program Endometriosis is an estrogen-dependent inflammatory condition in women that is characterised by the ectopic growth of endometrial glands and stroma outside of the uterine cavity. Although there exists many theories for the pathogenesis of endometriosis, none has been successively confirmed as a direct cause for disease development. The human body comprises a diverse microflora across all tissues that can have fundamental roles in health and disease. The microbial flora in a healthy individual can vary remarkably between anatomical sites due to the physical and... 
Quercetin Reduces Production of Hepatitis C Virus About 300 million individuals around the world are infected with the infectious disease hepatitis C, and approximately 1 to 2% of the population in the U.S. is infected. Hepatitis C can cause cirrhosis, scarring of the liver and finally liver failure. A substantial amount of infected individuals get liver disease or cancer of the liver. The existing standard treatment is interferon, and that has only a 50 percent rate of success. Complicating the 50 percent rate of failure are severe side effects that result in a lot of individuals discontinuing treatment. Researchers have... 
Pancreatic Cancer Association and Type 2 Diabetes Drugs According to a study, 2 drugs made use of for treating type 2 diabetes may be associated with a significantly higher risk of the development of pancreatic cancer and pancreatitis, and 1 of the drugs may be associated with an increased thyroid cancer risk. Researchers analyzed the FDA’s database for adverse events reported by individuals making use of the type 2 diabetes drugs exenatide and sitagliptin. A 6 times the increase in the odds ratio for reported pancreatitis cases with these drugs was found, in comparison to 4 other diabetes control... 
WHY ARE ANIMALS NEEDED IN BIOMEDICAL RESEARCH? Why are Animals Needed in Biomedical Research? The use of animals in some types of research is essential to the development of new and more effective methods for diagnosing and treating diseases that affect both humans and animals. Medical researchers need to understand health problems before they can develop ways to treat them. Scientists use animals to learn more about such problems, and to assure the safety of new medical treatments. Some diseases and health problems involve processes that can only be studied in living organisms. Animals are necessary to medical research because... 
Just as proper physical techniques should be part of every athlete’s safety routine, maintaining adequate nutrition and hydration is also important. By following basic nutrition and hydration tips, athletes can stay at peak performance before, during and after activity. Nutrition for Growth and Performance: Nutrients are fuel for the body. In order for our physical and mental health to remain strong and healthy, we need to consume a balanced diet of nutrients that can carry you through everyday life. Not only whilst performing sports activity, but before and afterwards. Important nutrients include: 
BIOMEDICAL RESEARCH AND ITS BROAD FIELDS 
