Submission Open: Journal of Clinical Nephrology and Therapeutics

Image Journal of Clinical Nephrology and Therapeutics publishes the manuscripts that are directly or indirectly based on variegated aspects of clinical nephrology, diabetic nephropathy, pediatric nephrology, renal physiology, renal histopathology, immunobiology, intensive care nephrology, and ischemic nephropathy. Journal of Clinical Nephrology and Therapeutics publishes the manuscripts that are directly or indirectly based on variegated aspects of clinical nephrology, diabetic nephropathy, pediatric nephrology, renal physiology, renal histopathology, immunobiology, intensive care ... Read More

KCa3.1 as a Novel Therapeutic Target for Diabetic Nephropathy

Image Diabetic nephropathy (DN), a devastating complication of diabetes mellitus, is a worldwide health, societal and economic problem. Tubulointersitial fibrosis has been shown to be the final common pathological consequence of almost all forms of chronic progressive renal disease, including diabetic nephropathy. Numerous pathways have been identified in the pathogenesis of this disease, but clinical strategies based on these pathways for the management of diabetic nephropathy remain unsatisfactory, as the number of diabetic patients with nephropathy continues to increase. New treatment modaliti... Read More

Recent trends in Biochemistry and Biotechnology

Image ADF Recent scientific era has witnessed a tremendous progression in the field of medical sciences due to development in allied fields of biotechnology and biochemistry. New techniques are constantly being introduced leading to the production of remarkable and medicinally valuable molecules, to alter hereditary traits of plants and animals, for diagnosis of various diseases and finally finding novel ways to cure them. The advancement made in the field of biotechnology has resulted in the development of a new class of potential drugs. It also helps in cloning and expression of various prophyl... Read More

Inhibition of LIM Kinase Inhibits Cancer Growth

Image The LIM kinase family of serine protein kinases contains two members, LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2). LIMK1 was first isolated from olfactory epithelial cell lines, and LIMK2 from a rat cDNA library using human LIMK1 cDNA as a probe. LIMK1 and 2 are structurally similar and share 50% amino acid homology, human and mouse LIMK1 share 95% amino acid homology. The amino terminus of LIMK contains two double zinc finger LIM domains, followed by a PDZ domain. Both domains are involved in protein-protein interaction. The C-terminus end of the molecule contains the catalytic active ki... Read More

Supportive and Innovative Hands to Improve advancement’s in Cardiovascular Medicines

Image On behalf of the Journal of Cardiovascular Medicine and Therapeutics, as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been ten long years we have started the Journal, now and we are privileged to welcome Analytical Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to the Journal of Cardiovascular Medicine and Therapeutics. ... Read More

Innovative Hands to Improve advancement’s in Cardiovascular Medicines

Image On behalf of the Journal of Cardiovascular Medicine and Therapeutics, as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been ten long years we have started the Journal, now and we are privileged to welcome Analytical Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to the Journal of Cardiovascular Medicine and Therapeutics. ... Read More

Predictors of Intradialytic Hypertension in Chronic End Stage Renal Dialysis

Image Patients on chronic maintenance dialysis have an alarmingly high mortality of approximately 15-20%. This rate is mainly due to cardiovascular comorbidity and, secondarily in part to the increasing prevalence of changes in blood pressure. These blood pressure changes are the most common complications that occur in these patients, most commonly hypotension, with Intradialytic Hypertension (IDH) occurring second. This single center, hospital based prospective observational cohort, research study investigated on (a) the prevalence of IDH and (b) determine the demographic, clinical profile and m... Read More

Gastrorenal Axis in the Control of Body Sodium Homeostasis

Image Organ to organ communication is important in the maintenance of normal fluid and electrolyte balance and blood pressure (BP). The gastrointestinal tract and the kidney are major organs involved in this process. Neural mechanisms and gut hormones mediate the natriuretic of an oral sodium load. The flow of sodium into the sodium channels of the stomach antrum activates a sequence of events, leading to G-cell-mediated increase in gastrin secretion and its release into the circulation. Of all the gut hormones circulating in the plasma, gastrin is the one that is reabsorbed to the greatest exten... Read More

Pregnancy among Women undergoing Chronic Hemodialysis

Image The pregnancy is told as a rare event among End-stage Renal Disease (ESRD) women undergoing chronic Hemodialysis (HD). This is mainly due to ESRD to be considered per se as a powerful method of contraception and sexual dysfunction is higher in women undergoing HD likely as a result of the cumulative effects of depression, fatigue, altered body image, medication side effects, and premature menopause, and the gestation in these women is frequently associated with poor fetal outcomes. However, in the last years the number of gestations among patients undergoing HD is increasing exponentially a... Read More

To Collaborate Scientific Professionals around the World- Cardiology

Image Cardiology is an important muscular organ in humans and other animals, pumps blood through the vessels of the circulatory system. In medicine, a case report is a detailed report of symptoms, diagnosis, treatment and follow-up of an individual patient. Heart case report may contain a demographic profile of patient but usually describe an unusual or novel occurrence. Different case report can be done such as case reports on cardiac arrest and disea... Read More

Assessment of drug discontinuation among adult patients who are taking antiretroviral treatment at Yeka Sub-City Woreda 9 and 10 health centers Addis Ababa, Ethiopia

Image Assessment of drug discontinuation among adult patients who are taking antiretroviral treatment at Yeka Sub-City Woreda 9 and 10 health centers Addis Ababa, Ethiopia Background:  Antiretroviral  therapy  has  led  to  a  substantial  reduction  in  HIV-associated  morbidity and  mortality.  Efficacy  of  antiretroviral  treatment  in  HIV/AIDS  is  showing  inhibition  of  viral replication and reduction of viral load to a point where... Read More

Chronic Pulmonary Obstructive Disease

Image Chronic Pulmonary Obstructive Disease The chronic obstructive pulmonary disease remains to be a vital cause of morbidity and mortality in the world. It is a worldwide health problem, with cigarette smoking being a significant risk factor commonly; other causes, such as exposure to outdoor and indoor air pollution, work-related risks, and infections, are moreover important. It is a major public health problem which probable to rank fifth in 2020 as a global disease problem according to a study published by the World Bank/World Health Organization. In this review, t... Read More

Ophthalmology Case Reports: Open Access

Image Ophthalmology Case Reports is scheduled to celebrate its 4th anniversary in the year 2020. The journal is devoted to convey and spread to its researchers around the world, the latest knowledge in the field of Ophthalmology.  It is an open-access journal that caters reliable information for clinical Ophthalmologists, and others in the form of original articles, review articles, case reports, short communications, etc. and might want to disperse information through high impact articles in ophthalmology. The Journal offers this unique opportunity of greater flexibilit... Read More

New Era in Diagnosis of Kidney Disorders Via NGS

Image Next-generation sequencing (NGS) or high-throughput DNA sequencing is a DNA sequencing technology that has revolutionized genomic survey. It has a remarkable impact on the clinical practice and diagnosis of genetic disorders through the sequencing of the entire human genome including all coding genes. The speed and high-throughput of NGS enable clinicians to focus on the diagnosis of genetic disorders at a rate never before possible. However, currently, there are some challenges in the application of this valuable technology such as the complexity of data analysis and interpretation. ... Read More

Bilateral Obstructive Uropathy

Image Journal of Clinical Nephrology and Therapeutics publishes the manuscripts that are directly or indirectly based on variegated aspects of clinical nephrology, diabetic nephropathy, pediatric nephrology, renal physiology, renal histopathology, immunobiology, intensive care nephrology, and ischemic nephropathy. Treatment of obstructive uropathy is a common urological referral. The two treatment options are nephrostomy tube or ureteric stent insertion. Both are equally effective at providing collec... Read More

Invitro Fertilization in Infertile Patients with Endometrial Cancer

Image To assess the effectiveness of intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF) and embryo transfer (IVF-ET) in infertile patients with early-stage endometrial cancer (EC) or atypical endometrial hyperplasia (AEH). Patients with well-differentiated, early-stage EC or AEH who achieved complete reversion of the endometrium after conservative treatment and who underwent IVF-ET between January 2012 and December 2015 were collected. The fertilization rate, implantation rate, pregnancy rate, and AEH/EC recurrence rate were measured. A total of 31 patient... Read More

Cardio-Nephrology

Image Journal of Clinical Nephrology and Therapeutics publishes the manuscripts that are directly or indirectly based on variegated aspects of clinical nephrology, diabetic nephropathy, pediatric nephrology, renal physiology, renal histopathology, immunobiology, intensive care nephrology, and ischemic nephropathy. Cardio-Nephrology: The need for more collaborative efforts between therapeutic clinical trials and social health sciences to preclude cardiovascular disease complications i... Read More

Journal of Public Health Policy and Planning Successful Journey

Image Journal of Public Health Policy and Planning is established in the year 2013,"Journal of Public Health Policy and Planning" and is overwhelmed by the response from the academic and research contributors to publish with the journal and to take part in the year-long celebrations.  It is one of the most reputed journals of Allied academies group, known for its strong association with various Alzheimer's societies and agencies engaged in cutting edge rese... Read More

Clinical and Therapeutic Treatment on Kidney Diseases

Image  Journal of Clinical Nephrology and Therapeutics is a peer-reviewed scientific open access journal that publishes original research articles, review articles, and clinical studies focusing on the prevention, diagnosis, and management of kidney diseases and associated disorders. It has a special emphasis on the needs of Clinical Nephrologists and those in developing countries. The journal publishes reviews and papers of international inte... Read More

Discount to Researchers for Article Processing Charges on 3rd Anniversary

Image Journal of Advanced Surgical Research (ISSN 2591-7765) commemorates its 3rd anniversary in the year 2020. Journal of Advanced Surgical Research is an upcoming journal that specializes in clinical surgical practices, researches, and teachings as well. This Journal majorly emphasizes the investigations or researches on surgical methods and analysis. It serves as a platform for academics, practitioners, regulators, and... Read More

Alarming the society on Kidney Diseases

Image Journal of Clinical Nephrology and Therapeutics is open access and peer-reviewed scientific journal. The journal serves as a bridge between scientific explorations and findings in the clinical field. And it also implementing the development of clinically applicable medical tools and techniques. Journal of Clinical Nephrology and Therapeutics publishes the manuscripts that are directly or indirectly based on variegated aspects o... Read More

Journal of Primary care and General Practice one step ahead in Protecting Life’s

Image Journal of Primary Care and General Practice is a peer-reviewed scientific publication that offers an open access forum to discuss the recent developments and innovative trends in the primary health care and general medical practice. Journal of Primary Care and General Practice, is established in the year 2018,"Journal of Primary Care and General Practice" and is overwhelmed by the response from the academ... Read More